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Breakthroughs

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Breakthroughs

Northwestern University Feinberg School of M

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Northwestern University Feinberg School of Medicine is a research-intensive medical school that fosters powerful collaborations on a thriving academic medical campus. We are driven by our mission to transform the practice of medicine and profoundly impact human health beyond the individual patient. We believe better answers only come from discovery.
 
Welcome to So You Want to Transform Healthcare, a podcast series created by Health2047 Inc., the innovation subsidiary of the American Medical Association. At Health2047, our mission is to find, found and scale innovative startups that transform healthcare at the system level before the AMA’s 200th anniversary in 2047. Innovating with intention is our business. In this podcast series, our Managing Director of Medical Affairs, Dr. M. Christine Stock—Professor Emerita from Northwestern’s Feinb ...
 
Host: Samir Kakodkar, MD - specialist in Crohn's disease and ulcerative colitis Medical School: Northwestern Feinberg School of Medicine Internal Medicine Residency: Rush University Medical Center Fellowship in Gastroenterology and Hepatology: Advocate Lutheran General Hospital Advanced Fellowship in Inflammatory Bowel Disease (Crohn's and Colitis): Northwestern Memorial Hospital Practice Location 7900 N Milwaukee Ave Suite 19, Niles, IL 60714 For appointments: 847-318-9595 Contact: samir3@g ...
 
Healthcare in America has been unevenly distributed since its founding. Our healthcare system has failed many Americans. In the wake of the pandemic, these disparities have been caste in sharp relief as the country struggles to address the system's failures. Equal Hope is a healthcare education, advocacy and navigation organization whose mission is to eliminate health disparities across Chicago. Our unique multi-pronged approach to systemic change has been recognized as one of the most succe ...
 
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show series
 
Millions of molecular proteins are swimming through our body's cells and many studies have discovered that these proteins are the main drivers of all human diseases. Scientists are now mapping proteins the way the Human Genome Project mapped genes. Northwestern's Neil Kelleher is at the forefront of the Human Proteoform Project and explains how it …
 
As a healthcare provider that spans across Illinois and Wisconsin, serving over 3 million patients per year and 75,000 employees, Advocate Aurora Health has a unique and broad perspective on the Social Determinants of Health and on health equity. Dr. Jackie Rouse explains how Advocate Aurora Health defines its sense of "community" by looking at its…
 
Sam Glassenberg, founder and CEO of Level Ex, speaks with host Dr. M Christine Stock, Managing Director of Medical Affairs at Health2047. Sam Glassenberg has been leading teams at the cutting edge of the video game industry. They discuss how Sam and his team at Level Ex harnesses video game technology and cognitive neuroscience to engage and train …
 
Regenerative nanomedicine is being used to develop new therapies for devastating conditions such as severe spinal cord injuries. Northwestern's Dr. Samuel Stupp is a pioneer in the field of regenerative nanomedicine and recently published a paper in the journal Science that details how a new injectable therapy uses synthetic nanofibers to reverse s…
 
John McIlwain and Dr. Summer Dewdney talk to Maria Pesqueira, the Executive Director of the Healthy Communities Foundation about their focus on health disparities. After re-evaluating their funding strategies, the McNeal Health Trust, which later became the Arthur Foundation, rebranded again to become the Healthy Communities Foundation. Given that …
 
Northwestern Medicine scientists have discovered one of the earliest signs of Parkinson's disease, proving that damaged neuronal mitochondria alone can cause symptoms of the disease, according to a study published in Nature. Senior author D. James Surmeier, chair of the Feinberg department of Neuroscience, who has over 30 years of experience in the…
 
People who are Black make up the largest group of minorities in need of an organ transplant. In 2019, Northwestern Medicine launched the African American Transplant Access Program to help address this problem. Founding director of the program Dinee Simpson, MD, talks about the barriers to organ transplant for Black patients and how she is working t…
 
Dr. Larry Goodman, retired CEO of Rush University Medical Center, and Dr. Omar Lateef explain how Rush re-evaluated the way it defined "community" as the healthcare institution sought to address "Community Health" needs. Dr. Lateef suggested that COVID-19 not only created a stress test for healthcare institutions across the country, it created a st…
 
Dr. Lee Fleisher, the CMS Chief Medical Officer and Director of the Center for Clinical Standards and Quality, speaks with host Dr. M Christine Stock, Managing Director of Medical Affairs at Health2047. Dr. Lee Fleisher is also a Professor of Anesthesiology, Critical Care, and Medicine at the University of Pennsylvania Perelman School of Medicine. …
 
Dr. Melissa Simon discusses her career and her focus on health equity from Northwestern's Feinberg School of Medicine with John McIlwain and Dr. Patricia Robinson. As a Latina, Dr. Simon brings particularly unique perspective to healthcare in Chicago, experiences that go back to her childhood. While growing up in Detroit, Dr. Simon saw relatives en…
 
This spring, the World Health Organization began using the Greek alphabet to label key variants of SARS-CoV-2. The Greek names make it easier to talk about variants with the public, but in the scientific community these variants are being discussed and studied at the molecular level to learn as much as possible about their evolution, replication an…
 
John McIlwain and Mary Richardson Lowry talk to authors Fernando De Maio & Maureen Benjamins about their new book, "Unequal Cities: Structural Racism & the Death Gap in America's Largest Cities." The core of their discussion centered on the importance of data in furthering the discussion around structural racism and poor health outcomes. "The disea…
 
While there are more treatments now than ever before for neuromuscular diseases like muscular dystrophy, patients who have very specific gene mutations associated with these diseases have few options. Dr. Elizabeth McNally says a discovery in her lab could lead to a new therapy for muscular dystrophy, including its rare forms.…
 
John McIlwain and Dr. Robin Jones from Rush University Medical Center talk with Dr. Linda Rae Murray, Cook County Health & Hospital Association's retired Chief Medical Officer about the role of "Trusted Messengers" in delivering equity across the healthcare system. Dr. Murray's remarkable career in Chicago and Canada give her a unique perspective o…
 
As the Delta variant of SARS-CoV-2 is causing breakthrough infections in some vaccinated people around the world, scientists at Northwestern Medicine are developing and studying potential next-generation COVID-19 vaccines that could be more effective at preventing and clearing breakthrough infections. Pablo Penaloza-MacMaster, assistant professor o…
 
As heart conditions like arrhythmia become increasingly common, heart monitoring is becoming an even more important tool for disease prevention and treatment. Northwestern Medicine cardiac electrophysiologist Rod Passman, MD, who has over three decades of experience in the field, reviews the history of cardiac monitoring and looks to the future. He…
 
This podcast is a deep dive into the recently published article "A Randomized Trial Comparing the Specific Carbohydrate Diet to a Mediterranean Diet in Adults With Crohn’s Disease." (also known as the Dine Study) published by Lewis, et al. Article link is here: https://pubmed.ncbi.nlm.nih.gov/34052278/ My guests are Dr. Meghana Doniparthi, gastroen…
 
Dr. Robin L. Jones from Rush University Medical Center, and a member of the Equal Hope Board of Directors and John McIlwain, Senior Director of External Affairs at Equal Hope discuss health equity with Dr. Aletha Maybank, the Chief Health Equity Officer of the American Medical Association. In light of the fall out from the Journal of the American M…
 
Dr. Joe Kvedar, professor of Dermatology at Harvard Medical School and Senior Advisor for virtual care at Mass General Brigham, speaks with host Dr. M. Christine Stock, Managing Director of Medical Affairs at Health2047. Dr. Joe Kvedar is internationally recognized for his leadership and vision in the field of connected healthcare. They discuss inn…
 
This is my second podcast with IBDCoach. We try to make sense of all the IBD diets, supplements and medications out there which can be so confusing! We also have a detailed discussion regarding Andrew's use of Ksharsutra (Ayurvedic Seton) to treat his fistula. I am not officially endorsing or recommending this service or Ksharsutra. You must discus…
 
Esophageal diseases are extremely common, and symptoms such as trouble swallowing, chest pain, regurgitation and choking diminish quality of life. There can also be psychosocial effects for patients with these diseases that includes hypervigilance — a heightened focus on physical symptoms — and symptom-specific anxiety such as fear of choking. Iden…
 
John McIlwain discusses Equal Hope's origins and impact on Chicago's healthcare marketplace with Dr. Larry Goodman, the retired CEO of Rush University Medical Center. According to John's conversation with Dr. Goodman, the best way to address the root causes of health disparities is through collaborative efforts; no one entity can achieve better hea…
 
Dr. Eric E. Whitaker, founder and CEO of Zing Health, speaks with host Dr. M. Christine Stock, Managing Director of Medical Affairs at Health2047. Dr. Whitaker is a nationally recognized authority on public health and an expert in the health issues of African American communities. They discuss how Zing Health provides healthcare solutions for medic…
 
Dr. David Ansell and John McIlwain interview Dr. Helene Gayle, the President & CEO of the Chicago Community Trust. Under Dr. Gayle's leadership, the Chicago Community Trust has identified the racial Wealth Gap as the primary strategic focus for the Trust. Drs. Ansell & Gayle discuss the policies that have lead to disparities in black and white weal…
 
A recent survey of more than 32,000 caregivers of Chicago Public School students found that around a quarter children and adolescents were described as stressed, anxious, angry or agitated in the months after remote learning began. Black and Latinx participants experienced significantly more of these stressors. Dr. Tali Raviv, associate professor o…
 
Dr. David Ansell & John McIlwain discuss the City's response to COVID-19 and what has been learned from the pandemic with Dr. Allison Arwady, Commissioner of the Chicago Department of Public Health. Dr. Arwady explains that one of the elements of the City's efforts to address vaccination disparities across Chicago's Black and Brown communities was …
 
Gerry Miller, founder and CEO of Cloudticity, a digital enablement partner empowering healthcare organizations to leverage the cloud, speaks with host Dr. M. Christine Stock, Managing Director of Medical Affairs at Health2047. From managing electronic health records to executing the New York State Department of Health's COVID-19 pandemic response, …
 
Recently, the director of the CDC officially recommended that pregnant women receive the vaccines for COVID-19. However, pregnant women are less likely than non-pregnant women to get vaccinated and are at greater risk of hospitalization and death from the disease. Emily Miller, MD, MPH, has been caring for pregnant patients at Prentice Women's Hosp…
 
Equal Hope interviews Ayesha Jaco, the Executive Director of West Side United. Equal Hope is the predecessor organization to West Side United. John McIlwain & Dr. Patricia Robinson delve into West Side United's genesis and learn more about how this cross-industry has developed a new approach to addressing Chicago's grave health disparities.…
 
Dr. Jesse Ehrenfeld, Director of the Advancing a Healthier Wisconsin Endowment and Senior Associate Dean and professor at the Medical College of Wisconsin School of Medicine, speaks with host Dr. M. Christine Stock, Managing Director of Medical Affairs at Health2047. They discuss how philanthropy can drive health innovation and the many projects th…
 
COVID-19 can be a multi-system disease, impacting many organs and the entire nervous system. Igor Koralnik, MD, has been investigating the neurologic symptoms of the disease and published the first study focused on long-term neurological symptoms in COVID-19 “long haulers.” He explains the study and what he is seeing in the Neuro COVID-19 Clinic at…
 
At the beginning of the pandemic, Daniel Batlle, MD, professor of medicine in the Division of Nephrology-Hypertension at Northwestern, proposed a hypothesis that soluble ACE2 could treat the SARS-CoV-2 virus and lead to full recovery and survival. Now, he has exciting preliminary results to share.By Northwestern University
 
Black men are more likely to get prostate cancer and more than twice as likely to die from the disease than other men. Dr. Edward Schaeffer has developed a research team to better understand this problem. In this show he talks about his latest discoveries, which are paving the way to precision medicine for aggressive prostate cancer. Dr. Schaeffer …
 
Charles Aunger, Managing Director for Technology at Health2047, speaks with host Dr. M. Christine Stock, Managing Director of Medical Affairs at Health2047. They discuss the current state of cybersecurity in healthcare organizations, the complexity of defending against attacks and, ultimately, where organizations should look to take healthcare cybe…
 
An early clinical trial in individuals with the deadly brain cancer glioblastoma showed an experimental spherical nucleic acid drug developed by Northwestern University scientists was able to penetrate the blood-brain barrier and trigger the death of tumor cells. Lead investigator Priya Kumthekar, MD, explains the results of the study.…
 
COVID-19 vaccines are being doled out across the nation, almost exclusively to adults. Pfizer's vaccine has been authorized for ages 16 and up and Moderna's vaccine for 18 and up. So when might younger children be vaccinated for COVID-19? And what needs to happen before then? Northwestern's William Muller, MD, PhD, offers insight.…
 
Dr. James Madara and Lawrence Cohen speak with host Dr. M. Christine Stock, Managing Director of ​Medical ​Affairs at Health2047. Dr. James Madara is CEO of the American Medical Association (AMA) and Lawrence Cohen, PhD, is CEO of Health2047. In celebration of Health2047’s 5th anniversary, they discuss how Health2047 was founded as an innovation su…
 
Since SARS-CoV-2 was discovered in Illinois over a year ago, Northwestern scientists have been tracking the evolution of the disease in the Chicago area. Ramón Lorenzo-Redondo, PhD, research assistant professor of Medicine in the Division of Infectious Diseases, is part of the team leading this work. He talks about the team's research, the new COVI…
 
Chris Komelasky and Neile Grayson speak with host Dr. M. Christine Stock, Managing Director of ​Medical ​Affairs at Health2047. Chris Komelasky is an advisor to Health2047 and Neile Grayson is a Managing Director of Corporate Portfolio and Project Management at Health2047. They discuss the importance of clinical research, the empowering impacts res…
 
In this episode, host Erin Spain takes a look and listen back on some of the top Feinberg research published in 2020. Hear how Northwestern scientists responded to COVID-19 while publishing high-impact papers unrelated to the pandemic and making vital discoveries across the research enterprise during a difficult time.…
 
Mark Bagnall, Executive in Residence at Health2047 and ​CEO of Phenomix Sciences, speaks with host Dr. M. Christine Stock, Managing Director of ​Medical ​Affairs at Health2047. They discuss Phenomix’s approach to obesity treatment and what entrepreneurs should know about the process of creating a startup company in the healthcare space.…
 
Daphne Li, Managing ​Director of ​Business ​Acceleration at Health2047 and ​Chief Operating ​Officer at First Mile Care, speaks with host Dr. M. Christine Stock, Managing Director of ​Medical ​Affairs at Health2047. They discuss First Mile Care for diabetes prevention and a new venture that will ease the financial and business-related burdens endur…
 
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