Manage episode 282046482 series 2505553
Dr. Knobbe began his practice of ophthalmology in 1994, after completing his residency training at the University of Colorado Health Sciences Center, in Denver, Colorado, USA. He was certified by the American Board of Ophthalmology in 1997 and has remained board-certified since then.
Eye physician and surgeon, Chris A. Knobbe, MD, had been in practice nearly 20 years when, in 2013, he asked himself the question, “Could macular degeneration be a ‘Westernized disease’? Could AMD be a disease that is the result of a Westernized diet?” That question would forever change his life.
The hypothesis that Dr. Knobbe would proffer holds that macular degeneration, which is the leading cause of irreversible vision loss and blindness in developed nations, is not only preventable but treatable in the early to moderate stages, with an ancestral diet.
0:09:24 Podcast Begins
0:12:39 200 years of nutritional research
0:23:09 Needs a title 60-sec audiogram
0:30:09 Timeline for Processed Food Introductions
0:36:44 Non-negotiable: Animal fats are essential
0:44:17 150 years of Vegetable Oil Consumption
0:49:07 Who's the real culprit?
0:51:46 Heart Disease Deaths vs Sturated fat and Vegetable Oil
1:05:32 Can linoleic acid contribute to coronary artery disease? https://www.researchgate.net/publication/15005994_Can_linoleic_acid_contribute_to_coronary_artery_disease
1:08:12 Why do we blame the carbs?
1:11:35 Sweden vs US adipose Linoleic Acid and obesity
1:14:02 The Case Of Japan
1:27:20 The problem is neither calories nor carbs
1:33:49 Is processed sugar harmful in and of itself? | What carbs to eat
1:43:36 The Case Of Okinawa
1:55:41 Diets could prevent many diseases Https://www.researchgate.net/publication/10673140_Diets_could_prevent_many_diseases
2:02:50 Lowering dietary linoleic acid reduces bioactive oxidized linoleic acid metabolites in humans https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467319/
2:03:29 Unsaturated fatty acids and their oxidation products stimulate CD36 expression in human macrophages https://www.researchgate.net/publication/11260045_Unsaturated_fatty_acids_and_their_oxidation_products_stimulate_CD36_expression_in_human_macrophages
2:04:13 Low-density lipoprotein rich in oleic acid is protected against oxidative modification: implications for dietary prevention of atherosclerosis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC54010/
2:06:00 A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans https://www.researchgate.net/publication/12880728_A_high_linoleic_acid_diet_increases_oxidative_stress_in_vivo_and_affects_nitric_oxide_metabolism_in_humans
2:10:50 Changes in Dietary Fat Intake Alter Plasma Levels of Oxidized Low-Density Lipoprotein and Lipoprotein(a) https://www.ahajournals.org/doi/10.1161/01.atv.0000118012.64932.f4
2:11:39 Where to find Chris Knobbe
Heart & Soil: www.heartandsoil.co
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